| 赵宏亮,张,杨,王启秀,等.电针对 I型超敏反应模型大鼠组胺及前列腺素 E含量影响[J].针灸临床杂志,2014,3(1):45-47 |
| 电针对 I型超敏反应模型大鼠组胺及前列腺素 E含量影响 |
| Effect of Electroacupuncture on HA and PGE2 of Type I Hypersensitive Rats |
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| DOI： |
| 中文关键词: 电针 Ⅰ型超敏反应 HA PGE2 大鼠 |
| 英文关键词: HA Electroacupuncture Type I hypersensitivity HA Rats |
| 基金项目: |
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| 中文摘要: |
| 目的：研究电针对Ⅰ型超敏反应模型大鼠的疗效。方法：将实验大鼠随机平均分成4组（每组为10只），分别为空白对照组、电针组、模型组、阳性药物组，通过卵白蛋白造成Ⅰ型超敏反应动物模型，模型建立后各组给予相应治疗，采用ELISA法测定大鼠血清中组胺（ HA）及前列腺素E2（ PGE2）含量，采用录像回放对大鼠的搔抓次数进行统计。结果：与模型组大鼠比较，电针组大鼠搔抓次数显著减少（P＜0．01），血清中组胺及前列腺素E2含量显著降低（P＜0．01），有显著性差异，电针组和阳性药物组比较无显著差异（ P＞0．05）。结论：电针对I型超敏反应模型中大鼠有一定疗效。 |
| 英文摘要: |
| Objective：To research the effects of electroacupuncture on inhibiting type I hypersensitivity for model rats.Methods：The experimental rats were randomly divided into four groups （ each group with 10 rats） , and they were normal group , model group , positive medicine group and electroacupuncture group .Through the ovalbumin type I hypersensitivity animal models were induced ,after the establishment of the model group it was given corresponding treatment .ELISA method was used for determination of rats＆#39;histamine （ HA） and prostaglan-din E2（PGE2） content in serum,and the video playback was to calculate the rats＆#39;scratching frequency statis-tics.Results：Compared with the model group , the electroacupuncture group had significantly reduced the num-ber of scratching （ P ＆lt;0 .01 ） , and the histamine and prostaglandin E 2 content significantly reduced in serum （ P＆lt;0.01 ） .They had a significant difference ,and electroacupuncture group and positive medicine group were no significant difference （ P＆gt;0 .05 ） .Conclusion：Electroacupuncture for type I hypersensitivity reaction model of rats has a certain curative effect . |
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