文章摘要
赵宏亮,张,杨,王启秀,等.电针对 I型超敏反应模型大鼠组胺及前列腺素 E含量影响[J].针灸临床杂志,2014,3(1):45-47
电针对 I型超敏反应模型大鼠组胺及前列腺素 E含量影响
Effect of Electroacupuncture on HA and PGE2 of Type I Hypersensitive Rats
  
DOI:
中文关键词: 电针  Ⅰ型超敏反应  HA  PGE2  大鼠
英文关键词: HA  Electroacupuncture  Type I hypersensitivity  HA  Rats
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作者单位
赵宏亮,张,杨,王启秀,等  
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中文摘要:
      目的:研究电针对Ⅰ型超敏反应模型大鼠的疗效。方法:将实验大鼠随机平均分成4组(每组为10只),分别为空白对照组、电针组、模型组、阳性药物组,通过卵白蛋白造成Ⅰ型超敏反应动物模型,模型建立后各组给予相应治疗,采用ELISA法测定大鼠血清中组胺( HA)及前列腺素E2( PGE2)含量,采用录像回放对大鼠的搔抓次数进行统计。结果:与模型组大鼠比较,电针组大鼠搔抓次数显著减少(P<0.01),血清中组胺及前列腺素E2含量显著降低(P<0.01),有显著性差异,电针组和阳性药物组比较无显著差异( P>0.05)。结论:电针对I型超敏反应模型中大鼠有一定疗效。
英文摘要:
      Objective:To research the effects of electroacupuncture on inhibiting type I hypersensitivity for model rats.Methods:The experimental rats were randomly divided into four groups ( each group with 10 rats) , and they were normal group , model group , positive medicine group and electroacupuncture group .Through the ovalbumin type I hypersensitivity animal models were induced ,after the establishment of the model group it was given corresponding treatment .ELISA method was used for determination of rats'histamine ( HA) and prostaglan-din E2(PGE2) content in serum,and the video playback was to calculate the rats'scratching frequency statis-tics.Results:Compared with the model group , the electroacupuncture group had significantly reduced the num-ber of scratching ( P <0 .01 ) , and the histamine and prostaglandin E 2 content significantly reduced in serum ( P<0.01 ) .They had a significant difference ,and electroacupuncture group and positive medicine group were no significant difference ( P>0 .05 ) .Conclusion:Electroacupuncture for type I hypersensitivity reaction model of rats has a certain curative effect .
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