文章摘要
智三针联合头针治疗卒中后血管性认知障碍的疗效及对VILIP-1、IGF-1水平影响
Effect of zhisanacupuncture combined with scalp acupuncture on vascular cognitive impairment after stroke and its effect on levels of VILIP-1 and IGF-1
投稿时间:2019-08-08  录用日期:2019-09-29
DOI:
中文关键词: 智三针  头针疗法  卒中后血管性认知障碍;VILIP-1、IGF-1水平;
英文关键词: three needles of wisdom  Scalp acupuncture  Vascular cognitive impairment after stroke  VILIP-1 and IGF-1 levels  
基金项目:]国家重点研发计划课题(NO.2017YFC1308504)
作者单位邮编
王琼芬* 1975-07-13 130850
王科 成都医学院附属第一医院 130850
王风波 成都医学院附属第一医院 130850
李让 成都医学院附属第一医院 130850
王娇娇 成都医学院附属第一医院 130850
李钰 成都医学院附属第一医院 130850
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中文摘要:
      目的:研究智三针联合头针治疗卒中后血管性认知障碍的疗效及对VILIP-1、IGF-1水平影响。方法:选取我院2016年1月-2018年12月收治的卒中后血管性认知障碍患者100例,根据随机数字表法分为两组各50例。对照组给予头针疗法,治疗组在对照组基础上给予智三针疗法,对比两组患者治疗后临床疗效、MMSE评分、MoCA 评分和ADL评分及血清VILIP-1、IGF-1水平。结果:经过治疗后,治疗组总有效率(94.00%)显著高于对照组(84.00%)(P<0.05);两组患者治疗后MMSE评分、MoCA 评分和ADL评分显著升高(P <0.05);并且治疗组升高程度较大(P<0.05);两组患者VILIP-1 水平显著降低,IGF-1水平显著升高(P <0.05);并且治疗组改善程度较大(P<0.05)。结论:采用智三针联合头针治疗卒中后血管性认知障碍,能够提高临床疗效,能够改善认知功能,值得在临床上推广应用。
英文摘要:
      objective: to study the effect of zhisan acupuncture combined with scalp acupuncture on vascular cognitive impairment after stroke and its effect on the levels of VILIP-1 and IGF-1. Methods: a total of 100 patients with vascular cognitive impairment after stroke admitted to our hospital from January 2016 to December 2018 were selected, and 50 patients were divided into two groups according to the random number table method. The patients in the control group were given head acupuncture therapy, while those in the treatment group were given three-needle therapy based on the control group. The clinical efficacy, MMSE score, MoCA score, ADL score and serum VILIP-1 and IGF-1 levels of the patients in the two groups were compared. Results: after treatment, the total effective rate (94.00%) of the treatment group was significantly higher than that of the control group (84.00%) (P<0.05). After treatment, MMSE score, MoCA score and ADL score were significantly increased in the two groups (P < 0.05). And the degree of increase in the treatment group was greater (P < 0.05). VILIP-1 level was significantly reduced and IGF-1 level significantly increased in the two groups (P < 0.05). And the improvement degree of the treatment group was greater (P < 0.05). Conclusion: the treatment of vascular cognitive impairment after stroke with the combination of zhi SAN acupuncture and scalp acupuncture can improve the clinical efficacy and cognitive function, and is worthy of clinical application.
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