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| 穴位埋线疗法治疗腹型肥胖伴轻度认知功能障碍的临床研究 |
| Clinical Study on Acupoint Catgut Embedding Therapy for Abdominal Obesity with Mild Cognitive Impairment |
| 投稿时间：2019-11-29 录用日期：2020-01-17 |
| DOI： |
| 中文关键词: 穴位埋线 针刺疗法 腹型肥胖 认知功能障碍 临床研究。 |
| 英文关键词: Acupoint catgut embedding Acupuncture therapy Abdominal obesity Mild cognitive impairment Clinical research. |
| 基金项目:1. 博士后研究人员落户黑龙江科研启动资助金项目：电针调节肥胖小鼠肠道菌群的机制研究(编号：LBH-Q18116)；2.博士后研究人员落户黑龙江科研启动资助金项目：电针抗慢性疲劳综合征大鼠海马、下丘脑蛋白表达差异及作用靶点实验研究(编号：LBH-Q18117)；3.青年科学：基于TGF-β/Smad信号通路研究NF-κΒ在电针抗慢性疲劳综合征中的作用及机制(编号：81704170)； 4.全国中医药创新骨干人才项目；5.黑龙江中医药大学校青年名中医培养项目。 |
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| 中文摘要: |
| 目的：观察穴位埋线疗法治疗腹型肥胖伴轻度认知功能障碍的临床疗效。方法：将64例患者按随机数字表法分为2组,即埋线组32例,针刺组32例。两组取穴相同,均治疗8周。观察两组患者治疗前后的腰围(WC)、臀围(HC)、腰臀比(WHR)、腰围身高比(WHtR)、体重(BW)、体重指数(BM1)、简易智力状态检查量表(MMSE)、蒙特利尔认知评定量表(MoCA)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-L)、低密度脂蛋白(LDL-L)、空腹血糖(FPG)、空腹胰岛素(FINS),比较两组患者的临床治疗效果。结果：埋线组总有效率为81.2%,针刺组为75.0%,两组进行临床疗效比较,差异无统计学意义(P＞O.O5)。两组治疗8周后各项指标与同组治疗前相比较,差异均具有统计学意义(P＜O.O5,P<O.O1)。埋线组治疗8周后各项指标与针刺组比较,差异均无统计学意义(P＞O.O5)。结论：穴位埋线疗法是治疗腹型肥胖伴轻度认知功能障碍的有效方法,可以减轻腹型肥胖、改善认知功能,同时调节脂代谢及胰岛功能,值得在临床中推广应用。 |
| 英文摘要: |
| Objective: To observe the clinical effect of acupoint catgut embedding therapy on abdominal obesity with mild cognitive impairment. Methods: 64 patients were divided into 2 groups according to the random number table, namely 32 patients in the embedding group and 32 patients in the acupuncture group. Both groups were treated for 8 weeks with the same acupoint selection. Observed two groups of patients before and after treatment of waist circumference (WC), hip circumference (HC), waist hip ratio (WHR), waist height ratio (WHtR), body weight (BW), body mass index (BMI) ,and Mini-mental State Examination scale (MMSE), Montreal Cognitive Assessment scale (MoCA), total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL-L), low density lipoprotein (LDL-L), fasting plasma glucose (FPG), fasting insulin (FINS), compare the clinical treatment effect of two groups of patients. Results: The total effective rate of the embedding group was 81.2%, and that of the acupuncture group was 75.0%. There was no statistically significant difference in clinical efficacy between the two groups (P >0.05).After 8 weeks of treatment, all the indicators in the two groups were statistically significant compared with those in the same group before treatment (P <0.05, P<0.01).After 8 weeks of treatment, there was no statistically significant difference between the indexes in the embedding group and the acupuncture group (P > 0.05). Conclusion: Acupoint catgut embedding therapy is an effective method to treat abdominal obesity with mild cognitive impairment, which can reduce abdominal obesity, improve cognitive function, and regulate lipid metabolism and islet function. |
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