文章摘要
滞动针法对膝骨关节炎患者关节功能及相关炎性标志物影响的临床随机对照试验<sub><sup>*</sup></sub>
Effect of Hysteretic acupuncture on joint function and related inflammatory markers in patients with knee osteoarthritis: a clinical randomized controlled trial
投稿时间:2020-01-06  录用日期:2020-01-17
DOI:
中文关键词: 膝骨关节炎  滞动针法  疼痛  关节功能  随机对照试验  疗效
英文关键词: Knee osteoarthritis  Hysteretic acupuncture  Pain  Joint function  Randomized controlled trial  Efficacy
基金项目:国家自然科学基金项目(面上项目,重点项目,重大项目)
作者单位邮编
汪国翔△ 广西中医药大学附属瑞康医院 530011
邓凯烽* 广西中医药大学附属瑞康医院 530011
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中文摘要:
      目的:观察滞动针法与普通针刺法两种疗法之间治疗膝骨关节炎的临床疗效差异,为临床提供更加有效的治疗方案。方法:将72例膝骨关节炎患者随机分为(滞动针法组)观察组和(普通针刺组)对照组各36例。两组均以犊鼻、内膝眼、足三里、阳陵泉、阴陵泉、血海、梁丘、鹤顶为主要穴位,行针得气后,两组均留针30min,1次/d。2组均14d为1个疗程,每个疗程休息2天,连续治疗2个疗程。观察两组治疗前后VAS评分、Lequesne指数评分、关节液相关炎性指标含量、中医证候疗效比较差异变化情况。结果:2组VAS评分、Lequesne指数评分、白细胞介素-6、肿瘤坏死因子-α水平在治疗2个疗程后均显著下降(P<0.05),并且观察组在降低VAS评分、Lequesne指数评分、白细胞介素-6、肿瘤坏死因子α水平等方面相较对照组更为显著(P<0.05);治疗后观察组总有效率为93.9%(31/33)高于对照组的84.4%(27/32)(P>0.05)。结论:滞动针法可有效缓解膝骨关节炎患者疼痛症状、促进关节功能恢复且不良反应少。
英文摘要:
      Objective: to observe the difference of clinical efficacy between hysteretic acupuncture and ordinary acupuncture in the treatment of knee osteoarthritis, and to provide more effective treatment for clinic. Methods: 72 patients with knee osteoarthritis were randomly divided into observation group (n = 36) and control group (n = 36). Both groups were treated with calving nose, inner knee eye, Zusanli, Yanglingquan, Yinlingquan, Xuehai, Liangqiu and Heding as the main acupoints. After acupuncture, both groups were given acupuncture for 30 min. once a day.2 group was a course of treatment for 14 days, each course of treatment was 2 days, and the course of treatment was 2 consecutive courses of treatment. The VAS score, Lequesne index score, the content of inflammatory indexes related to joint fluid and the curative effect of TCM syndromes were observed before and after treatment. Results: the levels of VAS score, Lequesne index score, IL-6 and tumor necrosis factor α in the two groups were significantly improved after two courses of treatment, and the levels of VAS score, Lequesne index score, IL-6 and tumor necrosis factor α content in the observation group were more significant than those in the control group (P<0.05). After treatment, the total effective rate in the observation group was 93.9% (31/33), which was higher than that in the control group (84.4%) (27/32) (P>0.05). Conclusion: hysteretic acupuncture can effectively relieve the pain symptoms of patients with knee osteoarthritis and promote the recovery of joint function with less adverse reactions.
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